HPLC Profile of Phenolic Contents, Antioxidant and Antidiabetic Activities of Methanolic Extract of the Leaves of Sarcocephalus latifolius (Bruce, Smith) Grown in North Central Geopolitical Zone, Nigeria
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Keywords

Sarcocephalus latifolius, Phenolic compounds, Antioxidant, Antihyperglycemic, HPLC.

How to Cite

A.T. Ajiboye* , O.T. Asekun and O.B. Familoni, A. A. , O. A. and O. F. (2020). HPLC Profile of Phenolic Contents, Antioxidant and Antidiabetic Activities of Methanolic Extract of the Leaves of Sarcocephalus latifolius (Bruce, Smith) Grown in North Central Geopolitical Zone, Nigeria. Jordan Journal of Chemistry (JJC), 15(3), 103-110. Retrieved from https://jjc.yu.edu.jo/index.php/jjc/article/view/445

Abstract

Preliminary phytochemical screening of the n-butanol fraction of the methanol leaf extract of Sarcocephalus latifolius was carried out; its phenolic contents were quantified by HPLC. The in vitro antihyperglycemic and antioxidant activities of the
fraction were evaluated. The results of the present study indicated that the leaves’ extract contained phytochemicals, like phenols, flavonoids, alkaloids and glycosides. Phenolic compounds, such as garlic acid, catechin, ferrulic acid, p-coumaric acid, apigen-7-glucose, kaemferol, quercetin and amentoflavone, were quantified by HPLC. Moreover, the fraction of leaves’ extract of S. latifolius demonstrated significant antioxidant and antihyperglycemic activities. The presence of these phytochemicals, especially phenols and flavonoids, in the leaves of S. latifolius therefore justifies its medicinal usefulness, as this plant has the
potential to protect oxidative stress-induced ailments 

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