Keywords
Clarithromycin; 3-Deoxyclarithromycin; Biotransformation; Aspergillus niger; Antibacterial activity
How to Cite
Al-Aboudi, A. (2010). Synthesis of 3-Deoxyclarithromycin through Biotransformation of Clarithromycin by Aspergillus niger and its Antibacterial Activity. Jordan Journal of Chemistry (JJC), 5(2), 131-138. Retrieved from https://jjc.yu.edu.jo/index.php/jjc/article/view/291
Abstract
Biotransformation of clarithromycin (1), by the plant pathogen Aspergillus niger ATCC 10549, produced one main metabolite identified as 3-deoxyclarithromycin (2). Testing the antibacterial activity against Staphylococcus aureus and Escherichia coli showed that compound 2 has a moderate activity against the tested bacteria.